What Causes Melasma? The Best Treatments for Skin Discoloration

What Causes Melasma? The Best Treatments for Skin Discoloration


What Causes Melasma and How to Treat It?

Melasma, often called "the mask of pregnancy," is characterized by facial hyperpigmentation or discoloration. Although typically harmless, it can significantly impact self-esteem and quality of life. Understanding what causes melasma and how to treat it is essential for managing this condition effectively.

What is Melasma?

Melasma appears as brown or gray-brown patches, primarily on sun-exposed areas such as the cheeks, forehead, nose, upper lip, and chin. It predominantly affects women, especially those with darker skin tones, and is less common in men. Knowing what causes melasma and how to treat it can help those affected manage their symptoms.

Hormonal Changes

Hormonal fluctuations are a leading cause of melasma. Pregnant women experience increased estrogen and progesterone levels, which stimulate melanin production, the pigment responsible for skin color. This explains why melasma is common during pregnancy and more prevalent in women. Birth control pills, hormone replacement therapy, and menopause-related hormonal changes can also trigger or worsen melasma. UV rays stimulate melanocytes, the cells that produce melanin. Those with melasma often notice their patches darken after sun exposure. Therefore, using broad-spectrum sunscreen and protective clothing is vital in preventing melasma from worsening.

Genetic Predisposition 

Genetics may predispose individuals to melasma, as it often runs in families. People with a family history of melasma are more likely to develop the condition. While specific genetic factors are still under study, inherited traits may influence skin pigmentation and susceptibility to environmental triggers. Understanding what causes melasma and how to treat it can be beneficial for those with a genetic predisposition.

Skin Irritants and Cosmetic Products

Certain skincare products and cosmetics with harsh chemicals or fragrances can worsen melasma. Ingredients like hydroquinone, alpha hydroxy acids (AHAs), and retinoids may increase skin sensitivity and inflammation, exacerbating melasma patches. It's crucial to choose gentle, non-comedogenic products suitable for sensitive skin and perform patch tests before introducing new products.

Thyroid Dysfunction 

Thyroid disorders, particularly hypothyroidism and hyperthyroidism, have been linked to melasma. Imbalances in thyroid hormone levels can disrupt melanin production, potentially leading to melasma development or exacerbation. Proper management of thyroid conditions may help alleviate melasma symptoms.

Hormonal Treatments and Medications 

Certain medications and treatments, including corticosteroids and photosensitizing drugs, can induce melasma or make existing patches more prominent. These medications may alter hormone levels, increase skin sensitivity to sunlight, or interfere with melanin production pathways. Patients should consult healthcare providers about potential side effects and alternative treatments if melasma develops or worsens during medication use.

Treatment of Melasma 

While prescription medications and professional treatments like chemical peels are available, several over-the-counter options can help treat melasma: 

Sunscreen: Broad-spectrum sunscreens with SPF 30 or higher protect against UV radiation and prevent melasma from worsening. Look for products with zinc oxide or titanium dioxide for physical sun protection. 

Topical Lightening Agents:

  • Alpha Hydroxy Acids (AHAs): Glycolic acid and lactic acid exfoliate the skin, promoting cell turnover and reducing the appearance of dark spots. OTC products containing AHAs can improve melasma over time. 
  • Azelaic Acid: Azelaic acid is a tyrosinase inhibitor that reduces melanin production when skin is overstimulated or irritated. 
  • Niacinamide: Also known as vitamin B3, niacinamide inhibits melanosome transfer, reducing pigmentation. OTC creams and serums containing niacinamide can improve melasma and overall skin tone.
  • Hydroquinone: Available in OTC formulations (2% or less), hydroquinone inhibits melanin production and lightens dark spots. It's typically applied twice daily for several weeks. 
  • Kojic Acid: Derived from fungi, kojic acid inhibits tyrosinase, an enzyme involved in melanin synthesis. It's often found in OTC creams and serums. 
  • Vitamin C: Ascorbic acid (vitamin C) possesses antioxidant properties and inhibits melanin production. Look for serums containing vitamin C for brightening effects. 

While melasma is not harmful, it can significantly impact self-confidence and quality of life. If you suspect melasma or notice changes in skin pigmentation, consult a dermatologist for a proper diagnosis and personalized treatment plan. Combining sun protection, gentle skincare, and targeted treatments can help manage melasma and minimize its impact on your skin's appearance and health.